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Table 2 Patterns of failure and survival in cervical cancers with pelvic, para-aortic and/or supraclavicular lymph node metastasis treated with PET-guided extended-field dose-escalating chemo-IMRT/3D-brachytherapy

From: Patterns of failure after use of 18F-FDG PET/CT in integration of extended-field chemo-IMRT and 3D-brachytherapy plannings for advanced cervical cancers with extensive lymph node metastases

Outcomes

Pelvic LAP

Paraaortic LAP

SC LAP

Total (%)

Dead/Total

5/26

12/31

6/15

23/72 (31.9)

In-field failure-only (cervix, lymph nodes)

2

5

1

8 (11.1)

Out-of-field failure-only (lymph node, bone and/or visceral metastases)

5

8

5

18 (25.0)

Both failures

1

2

0

3 (4.2)

Survival

 1-year DFS (%)

91.7

89.9

75.0

 3-year DFS (%)

78.5

55.8

75.0

 5-year DFS (%)

78.5

41.8

50.0

  1. Abbreviations: CCRT concurrent chemoradiotherapy, IMRT/IGRT intensity-modulated and image-guided radiotherapy, LAP lymphadenopathy, DFS disease-free survival, PET fluorodeoxyglucose position emission computed tomography