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Fig. 2 | BMC Cancer

Fig. 2

From: Patterns of failure after use of 18F-FDG PET/CT in integration of extended-field chemo-IMRT and 3D-brachytherapy plannings for advanced cervical cancers with extensive lymph node metastases

Fig. 2

Patterns of failure after 18F-FDG PET-guided RT planning. Pre-treatment combined RT planning scans of 3D-RT, IMRT and 3D-brachytherapy are fused to post-treatment recurrent 18F-FDG PET/CT scans to map the recurrent tumors in the initial RT treatment fields and dose distribution. The doses of external beam radiation and brachytherapy are transformed to EQD2 (equivalent dose to a 2-Gy fraction) for combination. a Out-of field recurrence and distant metastasis. RT dose distribution is demonstrated by colors. The lung metastasis confirmed by pathology is indicated by a white arrow. Note that the post-RT in-field structures show lower metabolic activity as compared to those in the pre-RT scan. (b) In-field recurrence. Note that the FDG-avid recurrent cervical tumor (white arrow) confirmed by pathology is located at the junctional zone of IMRT (EQD2 60 Gy) and brachytherapy (EQD2 85 Gy) in the parametrium

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BMC Cancer

ISSN: 1471-2407

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