Fig. 4
Ex vivo μCT reveals vascular response to cPLA2α inhibition. a Volume renderings of vasculature segmented from 150-slice sections of μCT images of representative control and treated tumors, color-coded by VC. Scale bar = 1 mm. b Normalized pooled histograms of VC in control and treated tumors. Bars indicate group medians, and error bars indicate median absolute deviations. c DNV maps corresponding to the central slices of the tumor sections depicted in a. Scale bar = 1 mm. d Normalized pooled histograms of DNV in control and treated tumors. Bars indicate group medians, and error bars indicate median absolute deviations. Dot plots of tumor-wise e FBV, f 90th percentile VC, and g 90th percentile DNV. Horizontal lines indicate group medians. * p < 0.05, ** p < 0.01, two-tailed Mann Whitney U test