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Table 2 One versus two tumor specimens

From: At least two well-spaced samples are needed to genotype a solid tumor

Tumor

Public mutations

Private mutations

Single biopsy

Single biopsy

Two biopsies

Two biopsies

Fraction of public mutations correctly called

Fraction of private mutations correctly called

Fraction of public mutations correctly called

Fraction of private mutations correctly called

K

14

42

1

0.38

1

1

S

24

13

1

0.38

1

1

P

30

7

1

0.29

1

1

X

52

17

0.98

0.71

1

1

O

45

6

0.98

0.50

1

1

A

36

25

0.94

0.79

1

1

C

40

32

0.98

0.55

1

1

M

6

17

1

0.10

1

0.29

N

72

29

0.96

0.42

0.99

0.10

W

95

5

0.97

0.29

1

0.80

U

50

12

0.95

0.54

1

1

T

36

19

0.85

0.52

1

0.95

Average

0.97

0.46

0.99

0.85