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Table 2 Comparison of 2188- and 101-gene centroid classifiers in the Lehmann et al. [11] validation cohorts

From: Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients

   

TNBCtype (2188 gene centroid model)

   

BL1

BL2

LAR

M

MSL

IM

Unclassified

101 gene centroid model

(A) All significantly classed cases

BL1

25

  

1

3

16

4

BL2

1

15

1

2

1

7

2

LAR

 

1

14

3

1

  

M

6

1

1

26

2

 

2

MSL

2

1

2

4

17

5

2

Unclassified

2

5

 

6

1

16

3

(B) Ambiguous cases unclassified

BL1

19

   

2

14

3

BL2

1

12

   

7

2

LAR

  

13

1

1

  

M

2

 

1

21

1

 

1

MSL

1

  

2

14

4

2

Unclassified

13

11

4

18

7

19

5

  1. In panel A, all cases are used. In Panel B, ambiguous cases—cases that showed an insignificant difference (via a Z-test) between subclasses—are placed in the unclassified group
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BMC Cancer

ISSN: 1471-2407

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