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Table 2 Comparison of 2188- and 101-gene centroid classifiers in the Lehmann et al. [11] validation cohorts

From: Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients

    TNBCtype (2188 gene centroid model)
    BL1 BL2 LAR M MSL IM Unclassified
101 gene centroid model (A) All significantly classed cases BL1 25    1 3 16 4
BL2 1 15 1 2 1 7 2
LAR   1 14 3 1   
M 6 1 1 26 2   2
MSL 2 1 2 4 17 5 2
Unclassified 2 5   6 1 16 3
(B) Ambiguous cases unclassified BL1 19     2 14 3
BL2 1 12     7 2
LAR    13 1 1   
M 2   1 21 1   1
MSL 1    2 14 4 2
Unclassified 13 11 4 18 7 19 5
  1. In panel A, all cases are used. In Panel B, ambiguous cases—cases that showed an insignificant difference (via a Z-test) between subclasses—are placed in the unclassified group