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Table 1 Overview of pancreatic panniculitides described in English literature between January 1994 and November 2014

From: Pancreatic panniculitis in a patient with pancreatic-type acinar cell carcinoma of the liver – case report and review of literature

Patient Ref. Age Sex Underlying condition Outcome of skin lesions/follow-up
1 our pat. 73 f ACC of the liver death ten weeks after first skin lesion
2 [53] 55 m metastatic pancreatic NEC n.r.
3 [54] 38 m acute pancreatitis resolution
4 [7] 63 m acute pancreatitis resolution
5 [55] 81 f hemosuccus pancreaticus death 19 weeks after first skin lesion
6 [56] 26 f acute pancreatitis resolution
7 [57] 27 f acute pancreatitis resolution
8 [58] 34 m chronic pancreatitis n.r.
9 [59] 63 f acute pancreatitis resolution
10 [60] 83 m pancreatic ACC resolution of skin lesions after surgery, death 34 months after first skin lesion
11 [60] 75 m Acute pancreatitis resolution
12 [60] 60 m Large pancreatic neoplasm n.r.
13 [61] 68 f metastatic pancreatic ACC death six months after first skin lesion
14 [62] 61 f acute pancreatitis resolution
15 [63] 63 f acute pancreatitis resolution
16 [64] 49 m acute pancreatitis resolution
17 [47] 69 m hepatic metastasis of previous-ly resected pancreatic ACC resolution after metastasectomy, follow-up n.r.
18 [65] 71 f chronic pancreatitis with pseudocyst n.r.
19 [66] 66 f serous cystadenoma of the pancreas n.r.
20 [67] 39 m chronic pancreatitis death six weeks after first skin lesion
21 [68] 20 f pseudopapillary pancreatic tumor, chronic pancreatitis death eleven weeks after first skin lesion
22 [8] 38 f acute pancreatitis resolution
23 [69] 56 f acute pancreatitis death within a few days
24 [70] 79 m pancreatic ACC n.r.
25 [71] 17 f acute pancreatitis resolution
26 [72] 54 m pancreatic ACC Response to octreotide, regression of skin lesions after resection, follow-up two months (i.e. eleven months after first skin lesion)
27 [73] 81 f pancreatic tumor with hepatic metastases n.r.
28 [74] 64 m anastomotic leakage after Whipple procedure death 50 days after first skin lesion
29 [75] 79 f pancreatic ACC regression after resection, follow-up 14 months after resection (i.e. 16 months after first skin lesion)
30 [35] 60 f pancreatic adenocarcinoma n.r.
31 [35] 58 m malignant neoplasia of the tail of the pancreas n.r.
32 [76] 44 f pancreas transplant rejection resolution
33 [77] 63 f metastatic pancreatic adenocarcinoma n.r.
34 [78] 38 m pancreatic pseudocyst-inferior vena cava fistula resolution after Roux-en-Y pseudocyst-jejunostomy
35 [40] 82 m pancreatic ACC death 2.5 months after first skin lesion
36 [46] 79 m pancreatic ACC death two months after first skin lesion
37 [79] 2,5 m acute pancreatitis with pseudocyst n.r.
38 [80] 45 m chronic pancreatitis resolution after placement of endoprothesis
39 [81] 18 w acute pancreatitis resolution
40 [82] 10 w acute pancreatitis with pseudocyst resolution after endosonographic cysto-gastrostomy
41 [83] 69 m gastric adenocarcinoma with pancreas metastasis death 14 weeks after first skin lesion
42 [84] 58 m pancreatic pseudocyst-portal vein fistula death five days after admission
43 [85] 84 m pancreatic tumor death two months after first skin lesion
44 [86] 40 m chronic pancreatitis n.r.
45 [87] 84 f acute pancreatitis, liver lesions ten years after resection of colonic carcinoma initially resolution, death three months later
46 [2] 65 f acute pancreatitis death from gangrenous cholecystitis
47 [2] 64 f acute pancreatitis resolution
48 [2] 70 f pancreatic carcinoma death
49 [2] 58 m pancreatic carcinoma death
50 [2] 21 f pancreatic carcinoma death
51 [2] 75 m acute pancreatitis death
52 [2] 75 f acute pancreatitis resolution
53 [2] 44 m chronic pancreatitis resolution
54 [2] 63 m pancreatic carcinoma death
55 [2] 72 m pancreatic carcinoma death
56 [2] 60 m pancreatic carcinoma n.r.
57 [88] 35 m chronic pancreatitis n.r.
58 [89] 7 m acute pancreatitis resolution
59 [14] 61 m metastatic NEC of unknown primary site death a few weeks after first skin lesion
60 [42] 50 f metastatic ACC regression of skin lesions and tumor under octreotide, gemcitabine, streptozocin and doxorubicin; return after discontinuation; response to restart of therapy; follow-up 9 months after first skin lesion
61 [90] 74 m pancreatic ACC death 3.75 months after first skin lesion
62 [91] 61 m metastatic ACC n.r.
63 [92] 79 m metastatic pancreatic NEC Regression under cefazolin, dexamethasone and NSAID; death 13 months after first skin lesion
64 [93] 50 m acute pancreatitis death 38 days after first skin lesion
65 [94] 4 m acute pancreatitis resolution
66 [11] 45 m acute pancreatitis Regression under NSAID and prednisone
67 [95] 72 m acute pancreatitis resolution
68 [96] 52 f pancreatic carcinoma death six months after first skin lesion
69 [97] 29 m acute pancreatitis resolution
70 [23] 75 f hepatic metastases of adeno-carcinoma of unknown origin death 15 weeks after first skin lesion
71 [6] 78 m metastatic pancreatic NEC death two months after first skin lesion
72 [6] 75 m pancreatic adenocarcinoma regression under irradiation, follow-up n.r.
73 [98] 67 f IPMN partial pancreatectomy, follow-up n.r.
74 [99] 51 m chronic pancreatitis regression of skin lesions under conservative treatment
75 [100] 49 f pancreas transplant rejection resolution
76 [101] 89 f acute pancreatitis resolution
77 [42] 59 m hepatic metastases of pre-viously resected pancreatic ACC death several weeks after first skin lesion
78 [102] 67 m metastatic pancreatic adenocarcinoma regression under irinotecan, cisplatin, mito-mycin; death twelve months after first skin lesion
79 [103] 62 f IPMN resection, follow-up n.r.
80 [22] 60 m metastatic pancreatic acinar cell cystadenocarcinoma death seven weeks after admission
81 [104] 13 m chronic pancreatitis with pseudocyst regression after cystogastrostomy
82 [41] 72 m pancreatic NEC regression after resection, no reappearance with liver metastases, death 15 months after first skin lesion
83 [25] 58 m HCC death four months after first skin lesion
84 [105] 88 m metastatic pancreatic NEC Death eight weeks after first skin lesion
85 [106] 42 f acute pancreatitis resolution
86 [107] 63 m chronic pancreatitis resolution after distal pancreatectomy and pancreatic duct dilation
87 [108] 34 m acute pancreatitis resolution
88 [109] 21 f acute pancreatitis death from retroperitoneal hemorrhage
89 [110] 61 f metastatic pancreatic ACC death one year after first skin lesion
90 [3] 70 f IPMN resolution after resection
91 [3] 53 f IPMN resolution after resection
92 [111] 37 f acute pancreatitis with pseudocyst resolution after surgery
93 [111] 50 m acute pancreatitis with pseudocyst resolution after stone extraction from the pancreatic duct
94 [112] 71 m pancreatic adenocarcinoma n.r.
95 [113] 60 f pancreatic ACC regression after distal pancreatectomy, follow-up 28 months after first skin lesion
96 [113] 54 m pancreatic ACC death six weeks after first skin lesion
97 [114] 56 m chronic pancreatitis n.r.
98 [115] 53 m actue pancreatitis resolution
99 [48] 67 m metastatic pancreatic ACC Regression after TACE of four liver metasta-ses, death 14 weeks after first skin lesion
100 [116] n.r. n.r. chronic pancreatitis resolution after placement of pancreatic duct stent
101 [117] 31 m acute pancreatitis resolution
102 [118] 57 f acute pancreatitis resolution
103 [119] 60 f pancreatic ACC resolution after resection, follow-up n.r.
104 [120] 41 m acute pancreatitis death 22 days after admission
105 [44] 79 f metastatic pancreatic ACC Death 20 weeks after first skin lesion
106 [121] 45 m chronic pancreatitis resolution
107 [122] 59 f acute pancreatitis resolution
108 [123] 81 m pancreatic ACC n.r.
109 [124] 69 m pancreatic ACC n.r.
110 [125] 15 f acute pancreatitis death nine days after first skin lesion
111 [126] 49 m acute pancreatitis regression under antibiotic treatment, then slight progression, follow-up seven weeks
112 [127] 66 m pancreatic ACC resolution after resection, follow-up n.r.
113 [128] 67 m chronic pancreatitis death two months after first skin lesion
114 [12] 69 m pancreatic ACC resolution after distal pancreatectomy and adjuvant radio-chemotherapy, follow-up 6 months
115 [129] 29 f acute pancreatitis resolution
116 [130] 29 m pancreatic pseudocyst-portal vein fistula no new lesions after surgery
117 [131] 75 m pancreatic tumor Death several months after first skin lesion
118 [131] 39 m chronic pancreatitis with pseudocyst n.r.
119 [132] 62 m acute pancreatitis resolution
120 [133] 77 f pancreatic tumor death five months after first skin lesion
121 [134] 54 f chronic pancreatitis resolution after ESWL and endoscopic dilation of the pancreatic duct
122 [135] 47 f acute pancreatitis resolution
123 [136] 7 m acute pancreatitis n.r.
124 [137] 69 m chronic pancreatitis with pseudocyst resolution
125 [138] 33 f acute pancreatitis n.r.
126 [139] 46 f chronic pancreatitis death four months after first skin lesion
127 [140] 55 m chronic pancreatitis n.r.
128 [5] 62 m acute pancreatitis resolution
129 [141] 61 f metastatic ACC resolution after surgery, follow-up n.r.
130 [142] 80 m pancreatic ACC resolution after surgery, death from metastatic disease after 18 months
131 [143] n.r. m pancreatic ACC n.r.