A novel anti-p21Ras scFv antibody reacting specifically with human tumour cell lines and primary tumour tissues

BMC Cancer

Table 1 Immunoreactivity of KGH-R1 mAb in human tumour cell lines

Tumour cell lines^a	Ras status^b	Western blot	Immunocytochemistry
QGY7703	Unknown	+	+
SMMC7721	Unknown	+	+
HepG2	N, mutant	+	+
BGC823	Unknown	+	+
MKN28	Unknown	+	+
HCT116	K, mutant	+	+
T24	H, mutant	+	+
SKOV3	Unknown	+	+
MDA-MB-231	K, mutant	+	+
MDA-MB-435	Unknown	+	+
MCF7	Unknown	+	+
HeLa	Wildtype	+	+
Hep2	Unknown	+	+
C8166	Unknown	+	+
K562	Unknown	+	+
Daud I	Unknown	-	-
HL60	N, mutant	-	-
MT4	Unknown	-	-
THP1	N, mutant	-	-

^aQGY7703, SMMC7721, HepG2: hepatocarcinoma; BGC853, MKN28: gastric cancer; HCT116: colorectal cancer; T24: bladder cancer; SKOV3: ovary cancer; MDA-MB-231, MDA-MB-435, MCF7: breast cancer; HeLa: cervical cancer; Hep2: laryngocarcinoma; C8166, K562, Daud I, HL60, MT4, THP1: leukaemia. ^bpublished data

ISSN: 1471-2407