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Table 5 Results of Cox proportional hazards analysis after adjusting for modalities, xerostomia, mucositis, dermatitis, body weight loss, dysphagia, fistula formation, anemia, leucopenia and thrombocytopenia

From: Impact of postoperative daily image-guided intensity-modulated radiotherapy on overall and local progression-free survival in patients with oral cavity cancer

 

5-year OS

5-year LPFS

Adjusted factors

Hazard ratio (HR)

95 % CI

p value

Hazard ratio (HR)

95 % CI

p value

IGRT vs Non-IGRT

0.46

0.22–0.97

0.042

0.18

0.06–0.56

0.003

aXerostomia (Acute)

0.92

0.45–1.88

0.813

1.32

0.53–3.33

0.554

Mucositis

0.73

0.42–1.27

0.270

0.93

0.41–2.11

0.856

Dermatitis

1.05

0.68–1.63

0.821

0.60

0.32–1.11

0.103

Body weight loss

1.31

0.68–2.54

0.427

0.32

0.09–1.13

0.076

Dysphagia

0.93

0.60–1.45

0.762

0.56

0.27–1.19

0.122

Fistula formation or superficial cases of skin dehiscence

0.00

0.00–0.00

0.978

0.00

0.00–0.00

0.985

Anemia

2.57

1.16–5.67

0.020

5.83

2.22–15.31

0.000

Leucopenia

1.08

0.67–1.73

0.766

0.85

0.47–1.54

0.588

Thrombocytopenia

0.62

0.29–1.33

0.220

0.59

0.23–1.38

0.206

  1. Abbreviations: CI confidence Interval, IGRT image-guided radiotherapy, LPFS local progression-free survival rate, OS overall survival rate
  2. aAcute xelostomia: Acute toxicity is defined as occurring < 90 days after beginning RT