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Table 5 Results of Cox proportional hazards analysis after adjusting for modalities, xerostomia, mucositis, dermatitis, body weight loss, dysphagia, fistula formation, anemia, leucopenia and thrombocytopenia

From: Impact of postoperative daily image-guided intensity-modulated radiotherapy on overall and local progression-free survival in patients with oral cavity cancer

  5-year OS 5-year LPFS
Adjusted factors Hazard ratio (HR) 95 % CI p value Hazard ratio (HR) 95 % CI p value
IGRT vs Non-IGRT 0.46 0.22–0.97 0.042 0.18 0.06–0.56 0.003
aXerostomia (Acute) 0.92 0.45–1.88 0.813 1.32 0.53–3.33 0.554
Mucositis 0.73 0.42–1.27 0.270 0.93 0.41–2.11 0.856
Dermatitis 1.05 0.68–1.63 0.821 0.60 0.32–1.11 0.103
Body weight loss 1.31 0.68–2.54 0.427 0.32 0.09–1.13 0.076
Dysphagia 0.93 0.60–1.45 0.762 0.56 0.27–1.19 0.122
Fistula formation or superficial cases of skin dehiscence 0.00 0.00–0.00 0.978 0.00 0.00–0.00 0.985
Anemia 2.57 1.16–5.67 0.020 5.83 2.22–15.31 0.000
Leucopenia 1.08 0.67–1.73 0.766 0.85 0.47–1.54 0.588
Thrombocytopenia 0.62 0.29–1.33 0.220 0.59 0.23–1.38 0.206
  1. Abbreviations: CI confidence Interval, IGRT image-guided radiotherapy, LPFS local progression-free survival rate, OS overall survival rate
  2. aAcute xelostomia: Acute toxicity is defined as occurring < 90 days after beginning RT
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