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Table 1 Patient characteristics

From: Impact of postoperative daily image-guided intensity-modulated radiotherapy on overall and local progression-free survival in patients with oral cavity cancer

  IMRT (non-IGRT) (No. = 79) HT (IGRT) (No. = 73) P value
Variable   No. of patients (%)  
Age (years)    
 Median 48 52 0.398
 Range 29–78 24–78
Gender    
 Male 78 (98.7 %) 70 (95.9 %) 0.274
 Female 1 (1.3 %) 3 (4.1 %)
Subsite    
 Oral tongue 25 (31.6 %) 35 (47.9 %) 0.348
 Buccal mucosa 34 (43.0 %) 25 (34.2 %)
 Alveolar ridge 8 (10.1 %) 7 (9.6 %)
 Retromolar trigone 5 (6.3 %) 3 (4.1 %)
 Floor of the mouth 2 (2.5 %) 2 (2.7 %)
 Hard palate 2 (2.5 %) 1 (1.4 %)
 Lip 3 (3.8 %) 0
Resection-margin status    
 Close or positive 39 (49.4 %) 42 (57.5 %) 0.313
 Negative 40 (50.6 %) 31 (42.5 %)
Extracapsular spread    
 Positive 13 (16.5 %) 19 (26.0 %) 0.148
 Negative 66 (83.5 %) 54 (74.0 %)
Perineural involvement    
 Positive 49 (62.0 %) 60 (82.2 %) 0.006
 Negative 30 (38.0 %) 13 (17.8 %)
Lymphovascular space involvement    
 Positive 31 (39.2 %) 46 (63.0 %) 0.003
 Negative 48 (60.8 %) 27 (37.0 %)
Pathology stage:    
Tumor stage    
 Stage I 6 (7.6 %) 8 (11.0 %) 0.532
 Stage II 12 (15.2 %) 12 (16.4 %)
 Stage III 18 (22.8 %) 15 (20.5 %)
 Stage IVA 43 (54.4 %) 38 (52.1 %)
Primary tumor stage    
 T1 14 (17.7 %) 13 (17.8 %) 0.768
 T2 22 (27.8 %) 25 (34.2 %)
 T3 18 (22.8 %) 11 (15.1 %)
 T4a 25 (31.6 %) 24 (32.9 %)
Regional lymph node stage    
 N0 39 (49.4 %) 38 (52.1 %) 0.302
 N1 15 (19.0 %) 7 (9.6 %)
 N2a 8 (10.1 %) 6 (8.2 %)
 N2b 14 (17.7 %) 20 (27.4 %)
 N2c 3 (3.8 %) 1 (1.4 %)
 N3 0 1 (1.4 %)
Adjuvant concurrent chemotherapy    
 Yes 67 (84.8 %) 65 (89.0 %) 0.442
 No 12 (15.2 %) 8 (11.0 %)  
RT dose    
 Median (range) 66 Gy (59.4–72 Gy) 66 Gy (60–70.2 Gy) 0.304
POTT    
 ≤13 weeks 46 (58.2 %) 61 (83.6 %) 0.001
 >13 weeks 33 (41.8 %) 12 (16.4 %)
OTTRT    
 ≤8 weeks 54 (68.4 %) 65 (89.0 %) 0.002
 >8 weeks 25 (31.6 %) 8 (11.0 %)
  1. Abbreviations: ECOG Performance Status Eastern Cooperative Oncology Group Performance Status, HT helical tomotherapy, IGRT image-guided radiotherapy, IMRT intensity-modulated radiotherapy, non-IGRT non-image-guided radiotherapy, OTTRT overall treatment time of radiotherapy, POTT package of overall treatment time
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