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Fig. 6 | BMC Cancer

Fig. 6

From: Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines

Fig. 6

Fold change in (a) MMP-2 and (b) MMP-9 enzyme levels after 48 h of treatment of Caco-2 and HCT-116 cells with metformin, 5-ASA or their combination. All data are expressed as mean ± SD of 3 separate experiments. The statistical significance of the results was analyzed using one way ANOVA followed by Tukey-Kramer multiple comparison test. a Significantly different from control, b from metformin c from 5-ASA (P <0.05)

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