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Fig. 2 | BMC Cancer

Fig. 2

From: Combined hepatocellular carcinoma and cholangiocarcinoma (biphenotypic) tumors: clinical characteristics, imaging features of contrast-enhanced ultrasound and computed tomography

Fig. 2

cHCC-CC in a patient with cirrhosis related to chronic hepatitis B infection. CA19-9 test was normal and AFP elevated (178.5 ng/ml) in discordance with presumptive imaging findings in the patient. Unenhanced ultrasound shows a hypoechoic nodule (a, arrow) of 2.7 cm in right lobe of the liver (RL). The nodule demonstrates peripheral rim-like enhancement in the arterial phase (b, 18 s after contrast agent injection, arrow) followed by quick (c, 37 s after injection) and marked washout (d, 82 s after injection) in the portal phase on CEUS, resembling the enhancement pattern of intrahepatic cholangiocarcinoma. Unenhanced CT scan reveals a hypodense nodule in right lobe of the liver (e, arrow). The nodule displays peripheral rim-like enhancement in the arterial phase (f, arrow) followed by stable and persistent peripheral rim-like enhancement in the portal (g) and the late phase (h, arrow), resembling the enhancement pattern of intrahepatic cholangiocarcinoma

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