Fig. 1From: Combined hepatocellular carcinoma and cholangiocarcinoma (biphenotypic) tumors: clinical characteristics, imaging features of contrast-enhanced ultrasound and computed tomographycHCC-CC in a patient with chronic hepatitis B. Simultaneous elevation of AFP (718 ng/ml) and CA19-9 (45.0U/ml) was detected in the patient. Unenhanced ultrasound shows a hypoechoic mass of 4.6 cm in right lobe of the liver (a, arrow). The mass displays heterogeneous hyperenhancement in the arterial phase (b, 26 s after contrast agent injection) followed by quick (c, 58 s after injection) and marked washout (d, 102 s after injection) in the portal phase on CEUS, resembling the enhancement pattern of intrahepatic cholangiocarcinoma. Unenhanced CT scan reveals a hypodense mass in right lobe of the liver (e, arrow). The mass displays heterogeneous hyperenhancemen in the arterial phase (f, arrow) followed by washout (g) in the portal phase and the late phase (h) on contrast-enhanced CT, resembling the enhancement pattern of HCCBack to article page