Fig. 6
From: MiRNA-146b-5p upregulates migration and invasion of different Papillary Thyroid Carcinoma cells
Overexpression of miR-146b-5p enhances cell spreading and formation of large lamellipodia in non tumor rat thyroid follicular cell line (PCCl3). Cells were seeded upon glass coverslips (18 mm) without and with Matrigel® coating (10 μg/ml) and cultured for 24 h. After this period, cells were fixed, stained for F-actin (green) and nucleus (blue) and analyzed by confocal microscopy. PCCl3-WT: non tumor rat thyroid follicular cell line, PC-CMV-ø: cell transfected with an empty vector, PC-CMV-146b: cell transfected with the miR-146-5p genomic region. Bars: 10 μm