Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

BMC Cancer

Table 3 Common differentially expressed microRNAs obtained by the comparison of tumors (primary and PDX) with normal bile duct

miR name	logFC	P.Value	Function
hsa-miR-142-3p	-1.14661	0.0049146
hsa-miR-199a-3p	-1.09606	0.0019647	Tumor suppressor
hsa-miR-199a-5p	-0.79526	0.0013074
hsa-miR-199b-5p	-0.76865	0.0030379
hsa-miR-148a-3p	-0.75023	0.0008472
hsa-miR-150-5p	-0.68957	0.000765	Migration/invasion
hsa-miR-23a-3p	-0.66533	0.0002675
hsa-miR-338-3p	0.767824	0.0037119	Proliferation
hsa-miR-222-3p	0.805174	0.0021683	Proliferation/invasion
hsa-miR-24-3p	0.828359	0.0002201	Proliferation/apoptosis
hsa-miR-92a-3p	0.853479	0.0053925
hsa-miR-106b-5p	0.878651	0.0057063
hsa-miR-130a-3p	0.92218	0.0052659
hsa-miR-16-5p	1.074798	0.0088751
hsa-miR-31-3p	1.075722	0.0051418
hsa-miR-20a-5p	1.089514	0.0034313
hsa-miR-1260a	1.191454	0.0081444
hsa-miR-193b-3p	1.222449	0.0002997	Tumor suppressor
hsa-miR-21-3p	1.236425	0.0045017	Oncogene
hsa-miR-17-5p	1.326209	0.0009174
hsa-miR-30a-5p	1.417434	0.0032646	Proliferation/migration
hsa-miR-200c-3p	1.502242	0.0011469	EMT-Transition
hsa-let-7b-5p	1.688168	0.0007466	Proliferation/apoptosis
hsa-miR-210-3p	2.014905	0.0002827
hsa-miR-31-5p	2.277681	9.30E-05	Cell cycle
hsa-miR-141-3p	2.387609	0.0065583
hsa-miR-720-v18.0	2.440588	0.0085144

ISSN: 1471-2407