BCNU | Control | |
---|---|---|
Patient sample (n) | 34 | 29 |
Age at 1st diagnosis (median; range) | 56 (22–76) | 62 (33–78) |
Sex (male: female; n) | 20:14 | 16:13 |
KPS (median; range) | 8 (4–10) | 6 (3–9) |
MGMT promoter hypermethylation (%) | 64,7 | 55,2 |
Overall survival (median: days (months)) | 480 (15) | 429 (14) |
Progression-free survival (median: days (months)) | 186 (6) | 180 (5) |
Survival after relapse (median: days (months)) | 266 (9) | 187 (6) |
Complete resection at 1st surgery (%) | 32,4 | 31 |
Radiotherapy at 1st diagnosis (%) | 100 | 100 |
TMZ at 1st diagnosis (%) | 14,7 | 17,2 |
Therapies other than BCNU at recurrence (re-resection, re-irradiation, TMZ, CCNU, thalidomide) | 38,2 | 24,1 |
BCNU cycles (% of patients) | N/A | |
- ≤6 | 88,2 | |
- 7–10 | 5,9 | |
- not determinable | 5,9 |