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Fig. 3 | BMC Cancer

Fig. 3

From: Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT

Fig. 3

Prolonged MTA pretreatment exacerbates cisplatin-induced cell cycle arrest and reduces the fraction of recovering cells. Flow cytometric analysis was performed at the indicated time points and subpopulations featuring either increased forward and side scatter intensity (F/S-high) or normal forward and side scatter intensity (F/S-low) were identified as indicated in Figure S2. Cell cycle analysis was performed as indicated in Figure S6. Data shown are the mean values and standard deviations of three experiments. *Percentage of total cell population (mean from three experiments)

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