Diagnosis of MetS requires: |
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Insulin resistance, identified by 1 of the following: |
Type 2 diabetes, Impaired fasting glucose, Impaired glucose tolerance, |
or for those with normal fasting glucose levels (<110 mg/dL), glucose uptake below the lowest quartile for background population under investigation under hyperinsulinemic, euglycemic conditions |
Plus any 2 of the following: |
Antihypertensive medication and/or high blood pressure (≥140 mm Hg systolic or ≥90 mm Hg diastolic) |
Plasma triglycerides ≥150 mg/dL (≥1.7 mmol/L) |
HDL cholesterol <35 mg/dL (<0.9 mmol/L) in men or <39 mg/dL (1.0 mmol/L) in women |
BMI >30 kg/m2 and/or waist:hip ratio >0.9 in men, >0.85 in women |
Urinary albumin excretion rate ≥20 μg/min or albumin: creatinine ratio ≥30 mg/g |