Fig. 5
TLN-1/2 knockdown inhibits tumor growth in vivo. MHCC-97 L cells (Blank), MHCC-97 L cells transduced with lentivirus-mediated TLN-1/2 shRNA (TLN-1/2 shRNA) or lentivirus-mediated scramble shRNA (Scramble shRNA) (5 × 107 cells/200 μl of PBS) were subcutaneously injected at the inguinal region of nude mice. a Tumor volume (mm3) was assessed by calipers every 3 days 20 days after cell inoculation. b The mice were sacrificed at 29 days after cell inoculation, and the tumors were extracted. Data are mean ± SD. *P < 0.05 vs. Blank; #P < 0.05 vs. scramble shRNA