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Fig. 5 | BMC Cancer

Fig. 5

From: Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERα-negative breast tumorigenesis

Fig. 5

Expression of Cdk4 and Ccnd1 (cyclin D1) are increased in DMBA-induced rat mammary adjacent tissues and tumors. Bars represent means ± SEM of quantitation (fold change of control) of (a) Cdk4 and (b) Ccnd1(cyclin D1) mRNA corrected for Gapdh mRNA as internal standard in control and DMBA-induced adjacent mammary tissues and tumors from 8 animals/group (n = 8). Different letters represent statistical differences (P < 0.05)

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