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Table 1 Patient characteristics for the overall population as well as stratified by 2 serum vitamin D categories

From: The relationship between circulating 25-hydroxyvitamin D and survival in newly diagnosed advanced non-small-cell lung cancer

Categorical variables

Overall population (n = 359)

Deficient: <20 ng/ml (n = 151)

Not deficient: > = 20 ng/ml (n = 208)

P-value

Gender

   

0.85

 Male

181

77 (42.5)

104 (57.5)

 

 Female

178

74 (41.6)

104 (58.4)

 

Stage

   

0.90

 III

94

39 (41.5)

55 (58.5)

 

 IV

265

112 (42.3)

153 (57.7)

 

CTCA hospital

   

0.04*

 Philadelphia, PA

50

13 (26)

37 (74)

 

 Zion, IL

269

119 (44.2)

150 (55.8)

 

 Tulsa, OK

40

19 (47.5)

21 (52.5)

 

Histologic subtypea

   

0.90

 Adenocarcinoma

268

114 (42.5)

154 (57.5)

 

 Squamous cell

67

28 (41.8)

39 (58.2)

 

 Others

19

9 (47.4)

10 (52.6)

 

SGAa

   

0.07

 Well-nourished

211

81 (38.4)

130 (61.6)

 

 Moderately-severely malnourished

124

60 (48.4)

64 (51.6)

 

ECOG scorea

   

0.02*

 0–1

233

88 (37.8)

145 (62.2)

 

 2–4

102

52 (51)

50 (49)

 

Season of diagnosis

   

0.004*

 Summer

93

34 (36.6)

59 (63.4)

 

 Fall

90

27 (30)

63 (70)

 

 Winter

72

34 (47.2)

38 (52.8)

 

 Spring

104

56 (53.8)

48 (46.2)

 

Smoking Statusa

   

0.006*

 Never

69

27 (39.1)

42 (60.9)

 

 Former

143

49 (34.3)

94 (65.7)

 

 Current

143

75 (52.4)

68 (47.6)

 

Vitamin D supplementation at diagnosis

   

0.92

 Yes

163

69 (42.3)

94 (57.7)

 

 No

196

82 (41.8)

114 (58.2)

 

Continuous variables

Overall population (n = 359)

Deficient: <20 ng/ml (n = 151)

Not deficient: > = 20 ng/ml (n = 208)

P-value

 Mean (SD) age (years)

57.4 (8.4)

57.1 (7.4)

57.6 (9.0)

0.62

 Mean (SD) vitamin D (ng/ml)

25.5 (15.3)

13.3 (4.1)

34.4 (14.3)

<0.001*

 Mean (SD) BMI (kg/m2)

25.8 (5.7)

25.5 (5.9)

26 (5.7)

0.43

 Mean (SD) serum albumin (g/dl)

3.6 (0.57)

3.5 (0.57)

3.6 (0.57)

0.06

  1. (SGA Subjective Global Assessment, ECOG Eastern Cooperative Oncology Group, CTCA Cancer Treatment Centers of America, PA Pennsylvania, IL Illinois, OK Oklahoma, BMI Body Mass Index, g/dl grams per deciliter, ng/ml nanograms per milliliter, kg/m2 kilograms per meter squared, SD Standard Deviation)
  2. *P < = 0.05, Values in parentheses are row percentages
  3. aMissing data (Histology = 5; SGA = 24; ECOG = 24; Smoking status = 4)