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Table 1 Summary of relative risks and prevalence (%) of exposure to modifiable reproductive factors in Korean women and data source
| Risk factors | Category | Relative risk (95 % CI) | Study design | Source | Prevalence (%)a | Source |
|---|---|---|---|---|---|---|
| Breast cancer | ||||||
| Pregnancy/age at first birth | Nulliparous | 1.06 (0.82-1.36) | Case–control study | SeBCS | 3 | KNHANES, 2005 |
| ≤23 years | 1.00 | 36 | ||||
| 24 – 30 year | 1.13 (0.98-1.32) | 57 | ||||
| ≥31 year | 1.27 (0.98-1.66) | 4 | ||||
| Total period of breast feeding | Never | 1.03 (0.87-1.21) | Case–control study | SeBCS | 17 (18b) | KNHANES, 2005 |
| ≤6 months | 1.28 (1.07-1.53) | 9 (10b) | ||||
| ≥7 months | 1.00 | 70 (72b) | ||||
| Oral contraceptive use | Never | 1.00 | Meta-anlaysis | SeBCS and [31] | 82 | KNHANES, 2005 |
| Ever | 1.31 (1.04-1.64) | 18 | ||||
| Hormone replacement therapy use | Never | 1.00 | 30 (95c) | KNHANES, 2005 | ||
| Ever | 1.16 (0.36-3.78) | Meta-anlaysis | SeBCS and [31] | 2 (5c) | ||
| Ovarian cancer | ||||||
| Pregnancy | Nulliparous | 1.42 (1.31-1.54) | Meta-anlaysis | Ko-EVE, [32–34, 36, 37, 40–42] | 3 | KNHANES, 2005 |
| Parous | 1.00 | 97 | ||||
| Breast feeding experience | Never | 1.17 (1.02-1.33) | Meta-anlaysis | Ko-EVE, [36, 39, 42, 43] | 17 (18b) | KNHANES, 2005 |
| Ever | 1.00 | 79(82b) | ||||
| Tubal ligation | No | 1.44 (1.33-1.56) | Meta-anlaysis | Ko-EVE and [44] | 75 (77b) | Ko-EVEd, 2009-2011 |
| Yes | 1.00 | 22 (23b) | ||||
| Oral contraceptive use | Never | 1.87 (0.89-3.94) | Meta-anlaysis | Ko-EVE and [45] | 82 | KNHANES, 2005 |
| Ever | 1.00 | 18 |
