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Table 1 Sensitivity of leukemia cell lines in response to THC

From: Dronabinol has preferential antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns

Patient No.

Phenotype

  

THC response

Entitiy

lineage dependency is marked (+) aberrantly expressed antigens are separately indicated

% viable cells at 50 μM

IC50 (μM)

 

T-lymphatic

B-lymphatic

myeloid

  

K562

+

87

62

M07e

+

81

59

HL60

CD4

+

15

38

Kasumi1

CD4

+

14

35

MV4-11

CD4

+

3

39

MOLM14

CD4

+

18

44

MOLM13

CD4

+

3

33

Jurkat

+

31

46