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Fig. 5 | BMC Cancer

Fig. 5

From: Role of HLA-G and extracellular vesicles in renal cancer stem cell-induced inhibition of dendritic cell differentiation

Fig. 5

Treatment of monocyte-derived cells with CD105+ EVs induced a release of sHLA-G. a Supernatants were harvested to detect sHLA-G production by ELISA, after 7 days of culture of monocyte-derived cells stimulated with EVs shed by renal cancer cells (CD105+ CSCs and CD105- TCs). Results were obtained from 3 independent experiments and expressed as mean ± SD. ANOVA with Newman Keuls multicomparison test was performed: ** p < 0.001 CD105+ EV Mo versus all the other conditions. b Representative Western Blot analysis showing the presence of HLA-G and Alix within EVs. Hsp90 was used as normalization. Four experiments were performed with similar results

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