Table 2 Association between clinicopathologic characteristics and OCT4 or SOX2 expression
From: Clinical significance of OCT4 and SOX2 protein expression in cervical cancer
| Â | OCT4 | Â | SOX2 | Â |
|---|---|---|---|---|
Mean Histoscore (95Â % CI) | p value | Mean Histoscore (95Â % CI) | p value | |
Diagnostic category | Â | <0.001 | Â | <0.001 |
 Normal | 113.3 (105.1–121.4) |  | 36.5 (32.3–40.8) |  |
 Low-grade CIN | 197.6 (177.4–217.7) |  | 40.0 (28.8–51.2) |  |
 High-grade CIN | 219.0 (211.3–226.8) |  | 91.7 (79.9–103.5) |  |
 Cancer | 208.5 (196.7–220.3) |  | 105.4 (91.8–119.1) |  |
FIGO stage | Â | 0.498 | Â | 0.529 |
  < IIA | 205.7 (191.6–219.7) |  | 108.1 (92.1–124.2) |  |
  > IIB | 215.1 (192.6–237.6) |  | 98.3 (71.5–125.1) |  |
Tumor differentiation | Â | 0.438 | Â | 0.112 |
 Well + moderate | 203.8 (187.7–219.8) |  | 112.8 (94.4–131.1) |  |
 Poor | 213.4 (195.3–231.4) |  | 90.1 (69.0–111.3) |  |
Cell type | Â | 0.450 | Â | 0.060 |
 SCC | 205.8 (192.4–219.2) |  | 111.7 (96.4–127.0) |  |
 Other | 217.2 (190.8–243.6) |  | 78.3 (69.0–111.3) |  |
Tumor size | Â | 0.868 | Â | 0.015 |
  ≤ 4 cm | 208.7 (194.2–223.2) |  | 116.5 (100.1–132.8) |  |
  > 4 cm | 206.5 (185.5–227.6) |  | 80.3 (56.3–104.2) |  |
LVSI | Â | 0.045 | Â | 0.106 |
 No | 195.3 (175.8–214.8) |  | 115.5 (95.4–135.6) |  |
 Yes | 220.1 (205.3–234.9) |  | 91.8 (71.2–112.5) |  |
LN metastasis | Â | 0.206 | Â | 0.879 |
 No | 202.6 (187.1–218.0) |  | 105.6 (88.6–122.7) |  |
 Yes | 221.0 (199.7–242.3) |  | 103.1 (75.6–130.6) |  |
HPV test in CIN | Â | 0.292 | Â | 0.907 |
 Negative | 246.8 (223.7–215.7) |  | 124.9 (81.5–168.7) |  |
 Positive | 227.9 (215.7–240.1) |  | 127.6 (110.5–144.6) |  |