Table 1 Top 10 most up- and downregulated genes induced by the 50-mW PDT regimen
From: Low-power photodynamic therapy induces survival signaling in perihilar cholangiocarcinoma cells
Gene: | Full name: | Function: |
|---|---|---|
CXCL1 | chemokine (C-X-C motif) ligand 1 | Cell proliferation, chemotaxis, inflammation |
IL8 | interleukin 8 | Angiogenesis, chemotaxis, inflammation |
C15orf48 | chromosome 15 open reading frame 48 | Â |
CXCL2 | chemokine (C-X-C motif) ligand 2 | Chemotaxis, inflammation |
UBD | ubiquitin D | Protein ubiquitination, aggresome formation, myeloid DC differentiation |
CSF2 | colony stimulating factor 2 | Macrophage activation, DC differentiation, immune response |
CCL20 | chemokine (C-C motif) ligand 20 | Chemotaxis, inflammation |
PDZK1IP1 | PDZK1 interacting protein 1 | Â |
CCL2 | chemokine (C-C motif) ligand 2 | Chemotaxis, inflammation |
FOS | FBJ murine osteosarcoma viral oncogene homolog | Inflammation, cellular response to ROS, DNA methylation |
LOC651309 | ||
THBS1 | thrombospondin 1 | Cell adhesion, extracellular matrix organization |
SOX21 | SRY (sex determining region Y)-box 21 | Transcription from RNA polymerase II promoter, SC differentiation |
TOX3 | TOX high mobility group box family member 3 | DNA-dependent transcription |
CBLN1 | cerebellin 1 precursor | Positive regulation of synapse assembly |
CGNL1 | cingulin-like 1 | Motor activity |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | Xenobiotic metabolic processes, drug metabolic processes |
SPOCK1 | testican 1 | Neuron migration, neurogenesis |
MMP10 | matrix metallopeptidase 10 | Proteolysis, extracellular matrix disassembly |
MMP1 | matrix metallopeptidase 1 | Proteolysis, extracellular matrix disassembly |