Table 1 Baseline patient data and univariate analysis of factors associated with survival at 60 months

Demographic data

Age (years)

59.65 ± 12.75

58.27 ± 12.58

0.614

Gender

Male

50 (64.9 %)

21 (70 %)

0.618*

Female

27 (35.1 %)

9 (30 %)

Pathologic factors

Colorectum

Colon cancer

45 (58.4 %)

15 (50 %)

0.389*

Rectal cancer

31 (40.3 %)

15 (50 %)

Tumor size (cm)

5.0 (2.0, 10.0)

3.7 (1.0, 10.0)

0.017

TNM stage

Tis

2 (2.6 %)

0

<0.001*

I

15 (19.5 %)

0

IIA

21 (27.3 %)

1 (3.3 %)

IIB

10 (13.0 %)

2 (6.7 %)

III

24 (31.2 %)

14 (46.7 %)

IV

5 (6.5 %)

13 (43.3 %)

Histologic type

Adenocarcinoma

67 (87.0 %)

26 (86.7 %)

0.436*

Mucinous adenocarcinoma

3 (3.9 %)

3 (10.0 %)

Signet ring cell carcinoma

1 (1.3 %)

0

Adenocarcinoma with component of mucinous adenocarcinoma

3 (3.9 %)

1 (3.3 %)

Adenocarcinoma with component of signet ring cell carcinoma

1 (1.3 %)

0

Other

2 (2.6 %)

0

Differentiation degree

Well differentiated

4 (5.2 %)

0

0.054*

Well or moderately differentiated

4 (5.2 %)

0

Moderately differentiated

54 (70.1 %)

24 (80.0 %)

Moderately or poorly differentiated

8 (10.4 %)

3 (10.0 %)

Poorly differentiated

5 (6.5 %)

1 (3.3 %)

Undifferentiated

1 (1.3 %)

1 (3.3 %)

Nodal metastasis

0 (0,12)

2 (0,9)

0.01

Ratio of nodal metastasis to retrieved nodes

0 % (0 %, 100 %)

8.93 % (0, 100)

0.03

Immunohistochemical factors

PCNA

60 % (0 %, 95 %)

52.5 % (10, 85)

0.129

nm23

0 = "(–)"

9 (11.7 %)

5 (16.7 %)

0.65*

1 = "(±)"

11 (14.3 %)

2 (6.7 %)

2 = "(+)"

51 (66.2 %)

22 (73.3 %)

3 = "(++)"

2 (2.6 %)

0

4 = "(+++)"

4 (5.2 %)

1 (3.3 %)

Cyclin D1

0 = "(–)"

14 (18.2 %)

3 (10.0 %)

0.03*

1 = "(±)"

28 (36.4 %)

5 (16.7 %)

2 = "(+)"

31 (40.3 %0

15 (50.0 %)

3 = "(++)"

3 (3.9 %)

6 (20.0 %)

4 = "(+++)"

1 (1.3 %)

1 (3.3 %)

Ki67

50 (0,95)

45 (5,90)

0.908

Maximum standardized uptake value

SUVmax

9.8 (4.4, 24.7)

13.6 (3.2, 34.2)

<0.001