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Table 3 Detection of CK20 positive tumor cells (CTC) in the blood of patients with rectal cancer after neoadjuvant RCTX

From: Cytokeratin 20 positive circulating tumor cells are a marker for response after neoadjuvant chemoradiation but not for prognosis in patients with rectal cancer

Variable

Category

Rate of CK20 positive CTC

χ2-test (p-values)

RCTX

Responder

27.2 % (6/22)

p = 0.030

 

Non-responder

54.4 % (31/57)

 

Tumor localisation

Upper 1/3

54.5 % (6/11)

p = 0.848

 

Middle 1/3

46.3 % (19/41)

 
 

Lower 1/3

44.4 % (12/27)

 

pN- Status

pN+

55.8 % (19/34)

p = 0.161

 

pN-

40 % (18/45)

 

UICC Stage

I

30,4 % (7/23)

p = 0.265

 

II

52.3 % (11/21)

 
 

III

51.7 % (15/29)

 
 

IV

66.6 % (4/6)