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Table 2 Univariable survival analysis of TSR and other prognostic factors

From: The prognostic significance of tumour-stroma ratio in endometrial carcinoma

 

Overall survival

Disease-free survival

Factor

HR (95 % CI)

P

HR (95 % CI)

P

LogTSR (continuous)

1.75 (1.04–2.94)

0.034

1.61 (0.98–2.64)

0.058

TSR ( ≥1.30 vs. <1.30)

2.51 (1.22–5.14)

0.012

2.18 (1.15–4.16)

0.017

Age (continuous)

1.07 (1.05–1.09)

<0.001

1.06 (1.05–1.08)

<0.001

Stage (FIGO 2009)

    

 I

Referent

Referent

Referent

Referent

 II

1.83 (1.00–3.36)

0.051

1.69 (0.94–3.01)

0.078

 III

3.21 (2.10–4.90)

<0.001

2.93 (1.96–4.39)

<0.001

 IV

11.44 (6.72–19.32)

<0.001

9.15 (5.52–15.15)

<0.001

Grade

    

 1

Referent

Referent

Referent

Referent

 2

1.61 (0.95–2.75)

0.080

1.53 (0.93–2.49)

0.092

 3

3.49 (2.22–5.49)

<0.001

2.95 (1.94–4.48)

<0.001

Lymphovascular invasion (yes vs. no)

3.00 (2.04–4.42)

<0.001

2.81 (1.95–4.04)

<0.001

  1. Univariable Cox proportional hazards regression for overall and disease-free survival. TSR was analysed both as a continuous variable (logTSR) and dichotomised according to the optimised cut-off
  2. Abbreviations: CI confidence interval, FIGO international federation of gynaecology and obstetrics, HR hazard ratio, TSR tumour-stroma ratio