From: Dietary calcium intake and the risk of colorectal cancer: a case control study
Control | Proximal colon | Distal colon | Rectum | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Total energy adjusted dietary calcium intake (mg/day) | No | No | Age-adjusted OR(95 % CI) | Multivariate ORa(95 % CI) | No | Age-adjusted OR(95 % CI) | Multivariate OR(95 % CI) | No | Age-adjusted OR(95 % CI) | Multivariate OR(95 % CI) |
Men | N = 1872 | N = 113 | N = 178 | N = 320 | ||||||
Q1 (<335) | 468 | 26 | 1.00 | 1.00 | 60 | 1.00 | 1.00 | 109 | 1.00 | 1.00 |
Q2 (335 - < 432) | 468 | 43 | 1.63(0.99–2.70) | 1.40(0.83–2.37) | 63 | 1.04(0.71–1.51) | 0.90(0.60–1.34) | 112 | 1.02(0.76–1.36) | 0.85(0.61–1.17) |
Q3 (432 - < 567) | 468 | 28 | 1.04(0.60–1.80) | 0.81(0.45–1.45) | 41 | 0.66(0.43–1.00) | 0.51(0.33–0.81) | 71 | 0.63(0.45–0.87) | 0.47(0.32–0.67) |
Q4 (≥567) | 468 | 16 | 0.58(0.31–1.10) | 0.35(0.17–0.74) | 14 | 0.22(0.12–0.40) | 0.13(0.07–0.26)c | 28 | 0.25(0.16–0.38) | 0.13(0.08–0.23)c |
P-value for trendb | 0.021 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | ||||
Women | N = 894 | N = 53 | N = 113 | N = 124 | ||||||
Q1 (<380) | 224 | 26 | 1.00 | 1.00 | 43 | 1.00 | 1.00 | 51 | 1.00 | 1.00 |
Q2 (380 - < 519) | 223 | 18 | 0.70(0.37–1.32) | 0.75(0.39–1.46) | 48 | 1.12(0.72–1.76) | 1.11(0.68–1.81) | 43 | 0.85(0.54–1.33) | 0.93(0.58–1.52) |
Q3 (519 - < 663) | 223 | 6 | 0.23(0.09–0.57) | 0.27(0.11–0.72) | 15 | 0.35(0.19–0.65) | 0.35(0.18–0.68) | 22 | 0.43(0.25–0.74) | 0.55(0.31–0.99) |
Q4 (≥663) | 224 | 3 | 0.11(0.03–0.38) | 0.13(0.03–0.48) | 7 | 0.16(0.07–0.37) | 0.12(0.05–0.32) | 8 | 0.16(0.07–0.34) | 0.20(0.09–0.47) |
P-value for trend | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 | <0.001 |