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Fig. 5 | BMC Cancer

Fig. 5

From: Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2

Fig. 5

The antitumor effect of PMS treatment in vivo. Mice were injected s.c. with 1.5 × 106 4T1 cells. a–c The fifth day after the injection, mice were treated daily with PMS at 200 mg/kg by oral gavage for 21 consecutive days. a Representative tumors at the end of the experiment, (b) tumor volume, (c) tumor weight at indicated time points after treatment was calculated. d Paraffin-embedded sections of control or treated tumor tissues from mice were analyzed by Ki67 IHC staining. e Quantitative analysis of Ki67 staining corresponding to the images in d. Data represent the mean ± S.D. of three independent experiments. Scale bar = 25 μm. The ** indicates significance different. The *** indicates extremely significance different

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