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Table 2 Cancer pathway-related and apoptosis-related genes significantly altered in Caki-1

From: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma

Refseq

Symbol

Description

Fold Change

Cancer pathway-related genes

NM_005994

DKC1

Dyskeratosis congenita 1, dyskerin

0.4918

NM_002982

OCLN

Occludin

0.4816

NM_001147

FASLG

Fas ligand (TNF superfamily, member 6)

0.4107

NM_005983

MKI67

Antigen identified by monoclonal antibody Ki-67

0.3950

NM_001315

LPL

Lipoprotein lipase

0.3660

NM_001950

LIG4

Ligase IV, DNA, ATP-dependent

0.3572

NM_018975

CA9

Carbonic anhydrase IX

0.2484

NM_001002

CDC20

Cell division cycle 20 homolog (S. cerevisiae)

0.1879

Apoptosis-related genes

NM_005427

TP73

Tumor protein p73

4.3079

NM_004049

BCL2A1

BCL2-related protein A1

2.2191

NM_000595

LTA

Lymphotoxin alpha (TNF superfamily, member 1)

2.1273

NM_004938

DAPK1

Death-associated protein kinase 1

2.0505

NM_016252

BIRC6

Baculoviral IAP repeat containing 6

0.5000

NM_003805

CRADD

CASP2 and RIPK1 domain containing adaptor with death domain

0.4386

NM_003842

TNFRSF10B

Tumor necrosis factor receptor superfamily, member 10b

0.4368

NM_003844

TNFRSF10A

Tumor necrosis factor receptor superfamily, member 10a

0.4087

NM_001924

GADD45A

Growth arrest and DNA-damage-inducible, alpha

0.3821

NM_014430

CIDEB

Cell death-inducing DFFA-like effector b

0.2975

NM_001066

TNFRSF1B

Tumor necrosis factor receptor superfamily, member 1B

0.2862

NM_003806

HRK

Harakiri, BCL2 interacting protein (contains only BH3 domain)

0.2360

NM_000594

TNF

Tumor necrosis factor

0.2126

NM_001561

TNFRSF9

Tumor necrosis factor receptor superfamily, member 9

0.1852

NM_001168

BIRC5

Baculoviral IAP repeat containing 5

0.1369