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Table 5 Multivariate Cox regression for cases with invasive carcinomas

From: Immunohistochemical evaluation of ROCK activation in invasive breast cancer

  Hazard ratio (95 % CI) P
Model 1
Age (year) 1.019 (1.001, 1.037) 0.044
Grade
 1 1  
 2 1.935 (0.258, 14.529) 0.521
 3 1.062 (0.132, 8.565) 0.955
Stage
 I 1  
 II 1.811 (0.673, 4.875) 0.240
 III 6.144 (2.264, 16.677) < 0.001
 IV 58.450 (9.985, 342.165) < 0.001
ER+ 0.403 (0.169, 0.963) 0.041
PR+ 1.768 (0.734, 4.262) 0.204
HER2+ 1.302 (0.688, 2.463) 0.418
Nuclear pROCKII ≥ 30 % 1.414 (0.715, 2.794) 0.319
Model 2
Age (year) 1.019 (1.000, 1.039) 0.050
Grade
 1 1  
 2 3.244 (0.442, 23.801) 0.247
 3 2.299 (0.297, 17.784) 0.425
ER+ 0.563 (0.241, 1.316) 0.185
PR+ 1.253 (0.532, 2.952) 0.605
HER2+ 1.315 (0.713, 2.425) 0.381
Nuclear pROCKII ≥ 30 % 2.116 (1.152, 3.888) 0.016
  1. Bold values indicate statistical significance (P < 0.05). ER, estrogen receptor; PR, progesterone receptor