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Table 3 Univariate and multivariate analyses predicting LNM using postoperative values

From: Difficulty of predicting the presence of lymph node metastases in patients with clinical early stage gastric cancer: a case control study

Variable Univariate Multivariate
OR (95 % CI) p-value OR (95 % CI) p-value
Gender Male 1 0.118   
  Female 1.46 (0.91–2.34)    
Agea   0.98 (0.96–0.99) 0.025 0.97 (0.94–0.99) 0.002
BMIa   1.00 (0.93–1.08) 0.977   
Gross type 0-I, IIa 1 <0.001   
  IIb 0.51 (0.13–2.28)    
  IIc, III 0.92 (0.28–3.09)    
  AGC 8.33 (2.37–29.29)    
Histology Pap, WD, MD 1 0.001   
  Muc, PD 2.65 (1.51–4.64) 0.001   
  Sig 0.86 (0.45–1.66) 0.654   
  CLS 0.0 (0.00–0.00) 0.999   
Ulcer Negative 1 0.113   
  Positive 1.52 (0.91–2.54)    
Location Upper third 1 0.145   
  Lower or middle third 0.63 (0.33–1.18)    
Tumor sizea   1.03 (1.02–1.05) <0.001 1.02 (1.01–1.04) <0.001
T-stage Mucosa 1 <0.001 1 <0.001
  Submucosa 5.13 (2.63–9.99) <0.001 5.44 (2.76–10.71) <0.001
  Proper muscle 11.73 (4.90–28.08) <0.001 10.23 (4.21–24.84) <0.001
  Subserosa 192.0 (36.82–1001.32) <0.001 149.40 (27.21–820.33) <0.001
  Serosa invasion 42.0 (13.11–134.56) <0.001 28.62 (8.32–98.42) <0.001
  1. aAnalyses were performed using continuous values
  2. LNM lymph node metastasis, OR odds ratio, CI confidence interval, BMI body-mass index, Pap papillary adenocarcinoma, WD well differentiated adenocarcinoma, MD moderately differentiated adenocarcinoma, Muc mucinous adenocarcinoma, PD poorly differentiated adenocarcinoma, Sig signet cell ring carcinoma, CLS carcinoma with lymphoid stroma