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Fig. 7 | BMC Cancer

Fig. 7

From: KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin in prostate cancer models

Fig. 7

Histochemical and immunohistochemical analyses. Hematoxylin/Eosin and Trichromic staining was shown in PC3 xenografts treated with KPT-251 (100 mg/kg) and KPT-330 (10 mg/kg). In this panel was also shown the expression of K67, tunnel, CD31, Fas and CD68 staining, depicting respectively proliferation, apoptosis, vessel formation, cell death receptor and monocyte/macrophage presence

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