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Table 2 Correlation between disease recurrence and CD44s expression in patients with ampullary adenocarcinoma who underwent radical resection

From: Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44ν is an indicator for recurrence in advanced cancer

  Extent of CD44s expression P-value
  Negative or weak (< 25 %)a (n = 53) Moderate or dense (≥ 25 %)a (n = 41)
Liver metastasis 16 (30 %) 9 (22 %) 0.481
Locoregional recurrence 20 (38 %) 14 (34 %) 1.000
Peritoneal carcinomatosis 7 (13 %) 4 (10 %) 0.754
Bone metastasis 9 (17 %) 1 (2 %) 0.039
Other metastasis b 7 (13 %) 4 (10 %) 0.752
Total a,c 35 (66 %) 25 (61 %) 0.668
  1. aExcludes three patients who died due to surgical complications and one patient with stage IV disease during surgery
  2. bIncluding brain, lung, and ovary metastases
  3. cSome patients developed more than one kind of metastases