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Fig. 4 | BMC Cancer

Fig. 4

From: Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44ν is an indicator for recurrence in advanced cancer

Fig. 4

Expression of CD44s, CD44ν3-10, CD44ν6-10 and CD44ν3,ν8-10 in ampullary adenocarcinoma. a The expression of CD44s and its variants in ampullary adenocarcinoma and corresponding normal duodenal tissues was determined by RT-PCR. β-actin served as a positive control. The fold-change in CD44 isoform/β-actin was labeled below the band. CD44ν3-10 and CD44ν3,ν8-10 mRNA was low in patients without cancer recurrence and increased in those with cancer recurrence. Fold change of cancer/normal ratio of CD44ν6-10 was increased in those with cancer recurrence. b The cancer/normal ratio of CD44/β-actin expression was correlated with cancer recurrence

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