Fig. 2

A-07 and R-18 tumors differed in K ^trans, v _e, and ADC. a-b, K ^trans, v _e, and ADC images, and K ^trans, v _e, and ADC frequency distributions of a representative untreated A-07 tumor (a), and a representative untreated R-18 tumor (b). The images refer to the central axial section of the tumor, whereas the frequency distributions are based on the individual voxel values of all the sections of the tumor. Color bars show K ^trans, v _e, or ADC scales, scale bars are 2 mm, and the vertical lines in the frequency distributions indicate median values. c-e, K ^trans (c), v _e (d), and ADC values (e) in untreated A-07 and R-18 tumors. Colums, means of 9-13 tumors, bars, SEM. Statistical comparisons of the data were carried out by the Student’s t test or the Mann–Whitney rank sum test. Untreated A-07 tumors showed significantly higher, K ^trans, v _e, and ADC values than untreated R-18 tumors (P < 0.001)