Fig. 4

Analysis of CIP2A on phosphorylation of 43 key signaling molecules using phospho-array in H460 cell line. a Phospho-array analysis of the phosphorylation of key molecules in signaling pathways using Human phospho kinase array. Highlighted spots are molecules showing fold of change > 1.4 between H460 cell line and H460 overexpressing CIP2A cell lines. Fold of change is measured by densitometry. b Differentially phosphorylated molecules between H460 + vector and H460 + CIP2A with information regarding their fold of changes and phosphorylation site(s). JNK, c-Jun activated kinase (JNK); GSK α/β, glycogen synthasase kinase α/β; EGFR, epidermal growth factor receptor; Hck, hemopoietic cell kinase; FAK, focal adhesion kinase (FAK)