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Fig. 4 | BMC Cancer

Fig. 4

From: A prospective study on histone γ-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome

Fig. 4

Effect of clinical radiation on the expression of histone γ-H2AX and 53BP1 foci in blood lymphocytes. a DNA damage was assessed by means of the histone γ-H2AX and b 53BP1 assays before (up triangles) and after 5 clinical fractions in PBMCs derived from unselected (right triangles) RC patients compared with RC patients with an adverse (grade 3, down triangles) clinical GI reaction to RT. Filled squares represent the mean values (± SE) for the respective group. “n.s.” indicates that the difference was not highly significant (p > 0.05)

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