Colon | Rectum | |||||||
---|---|---|---|---|---|---|---|---|
Factor | RFS | DSS | RFS | DSS | ||||
Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |
P | P | P | P | |||||
Age (years): ≥70 | 0.75 | – | 0.59 | – | 0.23 | – | 0.045 | 0.70 |
Gender: male | 0.47 | – | 0.68 | – | 0.35 | – | 0.22 | – |
CEA (ng/ml): >5 | 0.50 | – | 0.69 | – | 0.24 | – | 0.34 | – |
pT: 3 vs. 4 | 0.0029 | 0.66 | <0.0001 | 0.0026 | 0.33 | – | 0.14 | – |
Tumor size (cm): <5 | 0.49 | – | 0.46 | – | 0.054 | 0.47 | 0.75 | – |
Histology: well/moderate | 0.71 | – | 0.49 | – | 0.51 | – | 0.48 | – |
pN: (+) | 0.0005 | 0.84 | 0.021 | 0.47 | <0.0001 | 0.079 | 0.22 | – |
Total LNs count: <12 | 0.41 | – | 0.95 | – | 0.03 | 0.062 | 0.23 | – |
LN ratio: >0.29 | <0.0001 | 0.73 | 0.40 | <0.0001 | 0.65 | 0.026 | 0.67 | |
Lymphatic invasion: (+) | 0.23 | – | 0.51 | – | 0.045 | 0.36 | 0.38 | – |
Venous invasion: (+) | 0.034 | 0.14 | 0.13 | – | 0.18 | – | 0.24 | – |
Chemotherapy: (−) | 0.13 | – | 0.031 | 0.35 | 0.53 | – | 0.39 | – |
iTD: (+) | <0.0001 | 0.052 | 0.0038 | 0.32 | <0.0001 | 0.0039 | <0.0001 | 0.021 |
nTD: (+) | <0.0001 | 0.075 | 0.26 | – | 0.017 | 0.047 | 0.65 | – |
ECLNI: (+) | 0.0013 | 0.02 | 0.22 | – | 0.093 | 0.025 | 0.31 | – |