Table 4 Regulatory importance of transcription factors in cell line model of androgen insensitivity
From: Network analysis of an in vitro model of androgen-resistance in prostate cancer
Nuclear Receptor | Network size LNCaP cells | Network size LNCaP-AI cells | Increased Influence in LNCaP-AI |
|---|---|---|---|
PGR | 1 | 53 | 52 |
RXRA | 3 | 52 | 49 |
RARG | 2 | 44 | 42 |
RORA | 0 | 30 | 30 |
NR4A3 | 1 | 29 | 28 |
NR5A2 | 0 | 27 | 27 |
ESR2 | 0 | 23 | 23 |
VDR | 18 | 41 | 23 |
NR2C1 | 0 | 22 | 22 |
ESRRG | 22 | 42 | 20 |