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Table 2 Accuracy of detecting CIN2+ for different sampling media in combination with three HPV testing methods

From: Feasibility and accuracy evaluation of three human papillomavirus assays for FTA card-based sampling: a pilot study in cervical cancer screening

Methods Sampling Medium HPV Prevalence Accuracy
(%) Sensitivity Specificity Positive Predictive Value Negative Predictive Value
  % (n/N) 95 % CI % (n/N) 95 % CI % (n/N) 95 % CI % (n/N) 95 % CI
HC2 FTA 22.8 91.7 (11/12) 76.1 ~ 100.0 79.5 (283/356) 75.3 ~ 83.7 13.1 (11/84) 5.9 ~ 20.3 99.6 (283/284) 98.9 ~ 100.0
Liquid 30.4 91.7 (11/12) 76.1 ~ 100.0 71.6 (255/356) 66.9 ~ 76.3 9.8 (11/112) 4.3 ~ 15.3 99.6 (255/256) 98.8 ~ 100.0
careHPV™ FTA 23.9 83.3 (10/12) 62.2 ~ 100.0 78.1 (278/356) 73.8 ~ 82.4 11.4 (10/88) 4.8 ~ 18 99.3 (278/280) 98.3 ~ 100.0
Liquid 28.8 83.3 (10/12) 62.2 ~ 100.0 73.0 (260/356) 68.4 ~ 77.6 9.4 (10/106) 3.8 ~ 15 99.2 (260/262) 98.1 ~ 100.0
Cobas®4800 FTA 39.4 91.7 (11/12) 76.1 ~ 100.0 62.4 (222/356) 57.4 ~ 67.4 7.6 (11/145) 3.3 ~ 11.9 99.6 (222/223) 98.8 ~ 100.0
Liquid 32.1 91.7 (11/12) 76.1 ~ 100.0 69.9 (249/356) 65.1 ~ 74.7 9.3 (11/118) 4.1 ~ 14.5 99.6 (249/250) 98.8 ~ 100.0
  1. 95 % CI 95 % confidence interval, FTA Whatman Indicating FTA Elute® card, HC2 Hybrid capture 2