Skip to main content

Table 1 Baseline characteristics between never-users and ever-users of human insulin

From: Prolonged use of human insulin increases breast cancer risk in Taiwanese women with type 2 diabetes

  Human insulin  
Variables Never-users Ever-users P value
  n % n %  
n = 482033 422235   59798   
Age (years)a 62.54 ± 12.22   63.70 ± 12.65   <0.0001
Diabetes duration (years)a 5.12 ± 2.52   7.12 ± 1.65   <0.0001
Obesity 6082 1.44 974 1.63 0.0003
Nephropathy 39290 9.31 19533 32.66 <0.0001
Hypertension 228224 54.05 46172 77.21 <0.0001
Chronic obstructive pulmonary disease 51257 12.14 16773 28.05 <0.0001
Cerebrovascular disease 51910 12.29 19239 32.17 <0.0001
Ischemic heart disease 86668 20.53 25673 42.93 <0.0001
Peripheral arterial disease 41898 9.92 17216 28.79 <0.0001
Eye disease 48952 11.59 17588 29.41 <0.0001
Dyslipidemia 182015 43.11 33585 56.16 <0.0001
Congestive heart failure 24242 5.74 11009 18.41 <0.0001
Other cancer prior to baseline 39359 9.32 7672 12.83 <0.0001
Pioglitazone 9581 2.27 3503 5.86 <0.0001
Rosiglitazone 38135 9.03 16488 27.57 <0.0001
Sulfonylurea 304121 72.03 54487 91.12 <0.0001
Meglitinide 27501 6.51 11588 19.38 <0.0001
Metformin 259203 61.39 53420 89.33 <0.0001
Acarbose 33979 8.05 14763 24.69 <0.0001
Statin 97657 23.13 23400 39.13 <0.0001
Fibrate 77010 18.24 19220 32.14 <0.0001
Angiotensin converting enzyme inhibitor/angiotensin receptor blocker 169738 40.20 41504 69.41 <0.0001
Calcium channel blocker 133391 31.59 34541 57.76 <0.0001
Non-steroidal anti-inflammatory drugs 286403 67.83 56369 94.27 <0.0001
Estrogen 37775 8.95 8583 14.35 <0.0001
  1. aAge and diabetes duration are expressed as mean ± standard deviation