Development of a fluorescence–based multiplex genotyping method for simultaneous determination of human papillomavirus infections and viral loads

Table 1 Concordance rate of the BMRT HPV PCR assay with the HPV GenoArray test

Type^a	BMRT+/ GenoArray+	BMRT+/ GenoArray-	BMRT-/ GenoArray+	BMRT-/ GenoArray-	Positive coincidence rate	Negative coincidence rate	Total coincidence rate	Kappa value
HPV16	334	32	31	420	91.5 %	92.9 %	92.3 %	0.844
HPV18	129	10	18	660	87.8 %	98.5 %	96.6 %	0.881
HPV31	23	13	2	779	92.0 %	98.4 %	98.2 %	0.745
HPV59	16	19	0	782	100.0 %	97.6 %	97.7 %	0.617
HPV66	23	10	2	782	92.0 %	98.7 %	98.5 %	0.786
HPV53	37	20	2	758	94.9 %	97.4 %	97.3 %	0.757
HPV33	30	10	7	770	81.1 %	98.7 %	97.9 %	0.768
HPV58	73	13	17	714	81.1 %	98.2 %	96.3 %	0.809
HPV45	13	7	1	796	92.9 %	99.1 %	99.0 %	0.760
HPV56	12	53	2	750	85.7 %	93.4 %	93.3 %	0.284
HPV52	44	65	6	702	88.0 %	91.5 %	91.3 %	0.513
HPV35	9	15	1	792	90.0 %	98.1 %	98.0 %	0.521
HPV68	18	31	0	768	100.0 %	96.1 %	96.2 %	0.522
HPV51	9	33	0	775	100.0 %	95.9 %	96.0 %	0.341
HPV39	14	17	1	785	93.3 %	97.9 %	97.8 %	0.599
HPV6	51	22	3	741	94.4 %	97.1 %	96.9 %	0.787
HPV11	21	13	3	780	87.5 %	98.4 %	98.0 %	0.714
HPV81	29	22	4	762	87.9 %	97.2 %	96.8 %	0.675
Total	885	405	100	13316	89.8 %	97.0 %	96.6 %	0.760

ISSN: 1471-2407