Skip to main content

Table 3 Determination of IgA and AgG antibodies against H. pylori in gastric tissue from gastric cancer group by sampling site and cancer stage

From: Gastric cancer progression associated with local humoral immune responses

Immunoglobulin A
  Early gastric cancer n (5) Advanced gastric cancer n (12)  
Sampling site OD Median (IQR) OD Median (IQR) p value*
 Antrum 0.913 (0.578–0.937) 0.825 (0.689–0.945) NS
 Corpus 0.870 (0.688–0.957) 0.823 (0.735–1.039) NS
 Fundus 0.668 (0.668–0.772) 0.851 (0.717–1.115) NS
 Angular portion 0.637 (0.637–0.833) 0.881 (0.744–1.075) NS
p value (predetermined sites) NS NS  
 Mid-lesion 0.811 (0.474–0.827) 0.273 (0.150–0.632) NS
 Tumor margin 0.941 (0.762–1.147) 0.889 (0.484–0.965) NS
 At least 2 cm 1.175 (0.606–1.220) 0.869 (0.628–1.225) NS
 At least 5 cm 0.919 (0.753–0.928) 0.915 (0.642–1.308) NS
p value (tumor sites) NS 0.0023  
p value (predetermined sites + tumor sites) NS 0.0083  
Immunoglobulin G
  Early gastric cancer n (5) Advanced gastric cancer n (12)  
Sampling site OD Median (IQR) OD Median (IQR) p value*
 Antrum 0.375 (0.192–0.563) 0.182 (0.156–0.289) NS
 Corpus 0.473 (0.273–0.513) 0.285 (0.175–0.627) NS
 Fundus 0.516 (0.340–0.527) 0.299 (0.159–0.441) NS
 Angular portion 0.258 (0.236–0.550) 0.222 (0.142–0.348) NS
p value (predetermined sites) NS NS  
 Mid-lesion 0.285 (0.281–0.534) 0.151 (0.103–0.233) NS
 Tumor margin 0.508 (0.463–0.565) 0.221 (0.119–0.348) NS
 At least 2 cm 0.631 (0.296–0.926) 0.212 (0.133–0.501) NS
 At least 5 cm 0.439 (0.215–0.558) 0.188 (0.161–0.372) NS
p value (tumor sites) NS 0.0097  
p value (predetermined sites + tumor sites) NS NS  
  1. OD Optical Density, IQR interquartile range
  2. *Early gastric cancer vs Advanced gastric cancer
  3. NS not significant