Table 2 Determination of IgA and IgG antibodies against H. pylori in gastric tissue by sampling site and presence of gastric cancer
From: Gastric cancer progression associated with local humoral immune responses
Immunoglobulin A | |||
Non-cancer n (14) | Gastric cancer n (16) | ||
Sampling site | OD Median (IQR) | OD Median (IQR) | p value* |
Antrum | 0.176 (0.129–0.867) | 0.868 (0.578–0.945) | NS |
Corpus | 0.413 (0.134–0.737) | 0.836 (0.688–1.039) | 0.0068 |
Fundus | 0.267 (0.160–0.675) | 0.772 (0.668–1.115) | NS |
Angular portion | 0.275 (0.135–0.945) | 0.802 (0.637–1.051) | NS |
p value (predetermined sites) | NS | NS | |
Mid-lesion | . | 0.419 (0.152–0.736) | |
Tumor margin | . | 0.902 (0.536–0.975) | |
At least 2 cm | . | 0.976 (0.606–1.220) | |
At least 5 cm | . | 0.919 (0.753–1.293) | |
p value (tumor sites) | 0.001 | ||
p value (predetermined sites + tumor sites) | 0.0048 | ||
Immunoglobulin G | |||
Non-cancer n (14) | Gastric cancer n (16) | ||
Sampling site | OD Median (IQR) | OD Median (IQR) | p value* |
Antrum | 0.125 (0.107–0.615) | 0.200 (0.160–0.375) | NS |
Corpus | 0.199 (0.115–0.326) | 0.335 (0.226–0.627) | NS |
Fundus | 0.135 (0.116–0.462) | 0.342 (0.161–0.527) | NS |
Angular portion | 0.151 (0.103–0.608) | 0.247 (0.157–0.349) | NS |
p value (predetermined sites) | NS | NS | |
Mid-lesion | . | 0.193 (0.119–0.311) | |
Tumor margin | . | 0.300 (0.138–0.463) | |
At least 2 cm | . | 0.276 (0.165–0.631) | |
At least 5 cm | . | 0.215 (0.164–0.445) | |
p value (tumor sites) | 0.005 | ||
p value (predetermined sites + tumor sites) | NS | ||