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Table 2 Determination of IgA and IgG antibodies against H. pylori in gastric tissue by sampling site and presence of gastric cancer

From: Gastric cancer progression associated with local humoral immune responses

Immunoglobulin A
  Non-cancer n (14) Gastric cancer n (16)  
Sampling site OD Median (IQR) OD Median (IQR) p value*
 Antrum 0.176 (0.129–0.867) 0.868 (0.578–0.945) NS
 Corpus 0.413 (0.134–0.737) 0.836 (0.688–1.039) 0.0068
 Fundus 0.267 (0.160–0.675) 0.772 (0.668–1.115) NS
 Angular portion 0.275 (0.135–0.945) 0.802 (0.637–1.051) NS
p value (predetermined sites) NS NS  
 Mid-lesion . 0.419 (0.152–0.736)  
 Tumor margin . 0.902 (0.536–0.975)  
 At least 2 cm . 0.976 (0.606–1.220)  
 At least 5 cm . 0.919 (0.753–1.293)  
p value (tumor sites)   0.001  
p value (predetermined sites + tumor sites)   0.0048  
Immunoglobulin G
  Non-cancer n (14) Gastric cancer n (16)  
Sampling site OD Median (IQR) OD Median (IQR) p value*
 Antrum 0.125 (0.107–0.615) 0.200 (0.160–0.375) NS
 Corpus 0.199 (0.115–0.326) 0.335 (0.226–0.627) NS
 Fundus 0.135 (0.116–0.462) 0.342 (0.161–0.527) NS
 Angular portion 0.151 (0.103–0.608) 0.247 (0.157–0.349) NS
p value (predetermined sites) NS NS  
 Mid-lesion . 0.193 (0.119–0.311)  
 Tumor margin . 0.300 (0.138–0.463)  
 At least 2 cm . 0.276 (0.165–0.631)  
 At least 5 cm . 0.215 (0.164–0.445)  
p value (tumor sites)   0.005  
 p value (predetermined sites + tumor sites)   NS  
  1. OD Optical Density, IQR interquartile range
  2. *Non-cancer vs Gastric cancer
  3. NS not significant