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Table 2 Surgery time interval and tumor characteristics

From: Surgery time interval and molecular subtype may influence Ki67 change after core needle biopsy in breast cancer patients

Characteristic

1-2 days

3-4 days

≥5 days

P value

Age

   

0.067

 <40

5

5

10

 

 40-49

16

24

24

 

 50-70

32

70

53

 

 >70

2

14

21

 

Menstrual status

   

0.084

 Peri/pre-menopause

24

30

35

 

 Post-menopause

31

83

73

 

Breast surgery type

   

0.960

 Mastectomy (+/−reconstruction)

47

98

94

 

 Lumpectomy

8

15

14

 

Pathological type

   

0.973

 Invasive ductal carcinoma

49

101

96

 

 Invasive lobular carcinoma

3

5

4

 

 Others

3

7

8

 

Tumor size

   

0.110a

 Tx

2

2

1

 

 ≤2 cm

30

45

43

 

 2-5 cm

23

65

49

 

 >5 cm

0

1

5

 

Axillary lymph node

   

0.582

 Negative

28

67

60

 

 Positive

27

46

48

 

Histologic grading

   

0.821a

 I

0

3

3

 

 II

30

51

53

 

 III

15

41

34

 

 NA

10

18

18

 

Estrogen Receptor

   

0.732

 Negative

11

28

23

 

 Positive

44

85

85

 

Progesterone Receptor

   

0.357

 Negative

21

52

40

 

 Positive

34

61

68

 

Hormonal Receptor

   

0.822

 Negative

11

27

23

 

 Positive

44

86

85

 

HER2

   

0.797

 Negative

43

91

83

 

 Positive

12

22

25

 

Ki67 (%, mean)

   

0.222

 <20

20

55

54

 

 ≥20

35

58

54

 

Molecular subtype

   

0.738

 Luminal A

13

30

30

 

 Luminal B-HER2-

26

43

40

 

 Luminal B-HER2+

5

13

15

 

 Triple negative

4

18

13

 

 HER2 positive

7

9

10

 
  1. Abbreviation: NA not available
  2. aCalculated by Fisher’s exact test