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Table 4 Correlation between tumor expression of IAPs and caspases and clinicopahological features

From: Prognostic value of inhibitors of apoptosis proteins (IAPs) and caspases in prostate cancer: caspase-3 forms and XIAP predict biochemical progression after radical prostatectomy

  Procaspase-8 Cleaved caspase-8 Procaspase-3 Cleaved caspase-3 Caspase-7 Procaspase-9
  r p r p r p r p r p r p
Preoperative serum PSA 0.000 1.000 0.294 0.007* 0.076 0.494 −0.098 0.377 0.185 0.091 0.017 0.881
Pathological T stage 0.216 0.048* −0.056 0.611 −0.154 0.161 0.160 0.146 −0.023 0.833 −0.072 0.513
Clinical T stage 0.235 0.031* −0.003 0.979 −0.161 0.144 −0.055 0.617 0.121 0.237 −0.054 0.625
Gleason score 0.118 0.287 −0.006 0.954 0.013 0.904 0.107 0.331 0.289 0.008* −0.151 0.171
Perineural invasion 0.118 0.285 0.104 0.345 −0.023 0.834 0.027 0.808 0.007 0.951 −0.046 0.680
Node involvement −0.175 0.110 0.007 0.952 −0.110 0.318 0.147 0.183 0.250 0.022* 0.068 0.539
Positive surgical margins 0.160 0.145 −0.149 0.176 −0.277 0.011* −0.098 0.377 −0.037 0.738 0.133 0.229
Biochemical progresion 0.015 0.890 −0.126 0.254 −0.362 0.001* −0.364 0.001* 0.082 0.461 0.002 0.983
Survival 0.163 0.139 0.014 0.898 −0.161 0.142 −0.250 0.022* −0.202 0.065 −0.133 0.229
  1. Correlations between immunohistochemical variables (according to the stratification shown in Table 2) and preoperative serum PSA, pathological T stage, clinical T stage and Gleason score were evaluated by Spearman’s test (r, correlation coefficient). *p < 0.05. (Note: significant correlations after Bonferroni correction should be those with a p < 0.005)