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Fig. 1 | BMC Cancer

Fig. 1

From: Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis

Fig. 1

Phenotypic differences between breast cancer spheres and control HMEC spheres. a Confocal of HMEC (a, a’), SUM149PT (b, b’) and SUM1315MO2 (c, c’) spheres. Cells were seeded in a 6-well ultra-low attachment plate, grown for 8 days, and then confocal imaged at 10X magnification. Results shown are tiled shots of two different fields and the assay was performed in triplicate with n = 3. The (b) diameter and (c) perimeter of spheres was measured using the FV10-ASW3.0 software, and statistical significance was calculated with respect to HMEC. d Confocal images of secondary sphere cultures from SUM149PT (a) and SUM1315MO2 (b) with n = 3

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BMC Cancer

ISSN: 1471-2407

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