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Table 1 Demographic distribution of the nested cohort from the Endoscopy II prospective sample collection

From: Performance of the colorectal cancer screening marker Sept9 is influenced by age, diabetes and arthritis: a nested case–control study

Variable

 

Total

CRC

Adenoma

NED

  

299

128

21

150

Sex

Female

151

65 (51)

11 (52)

75 (50)

 

Male

148

63 (49)

10 (48)

75 (50)

Age

≤65

183

74 (58)

11 (52)

98 (65)

 

>65

116

54 (42)

10 (48)

52 (35)

Rectal bleeding

No

166

54 (42)

10 (48)

102 (68)

 

Yes

133

74 (58)

11 (52)

48 (32)

Anemia

No

250

102 (80)

19 (90)

129 (86)

 

Yes

49

26 (20)

2 (10)

21 (14)

Weightloss

No

211

81 (63)

17 (81)

113 (75)

 

Yes

88

47 (37)

4 (19)

37 (25)

Altered Defaecation

No

126

58 (45)

12 (57)

56 (37)

 

Yes

173

70 (55)

9 (43)

94 (63)

Abdominal Pain

No

172

72 (56)

17 (81)

83 (55)

 

Yes

127

56 (44)

4 (19)

67 (45)

Abdominal mass

No

283

119 (93)

0

143 (95)

 

Yes

16

9 (7)

0

7 (5)

Distention

No

241

103 (80)

21 (100)

117 (78)

 

Yes

58

25 (20)

0 (0)

33 (22)

Hypertension

No

183

81 (63)

10 (48)

92 (61)

 

Yes

116

47 (37)

11 (52)

58 (39)

Diabetes

No

280

117 (91)

16 (76)

147 (98)

 

Yes

19

11 (9)

5 (24)

3 (2)

Arteriosclerosis

No

243

108 (84)

19 (90)

116 (77)

 

Yes

56

20 (16)

2 (10)

34 (23)

Respiratory disease

No

267

117 (91)

21 (100)

129 (86)

 

Yes

32

11 (9)

0 (0)

21 (14)

Arthritis

No

281

120 (94)

20 (95)

141 (94)

 

Yes

18

8 (6)

1 (5)

9 (6)

Smoke#

No

123

47 (37)

12 (57)

64 (43)

 

Yes

 

81 (63)

9 (43)

86 (57)

Alcohol##

Normal

245

103 (80)

15 (71)

127 (85)

 

Abuse

54

25 (20)

6 (29)

23 (15)

BMI###

<18,5

10

4 (3)

1 (5)

5 (3)

 

18,5 to 25

162

70 (55)

10 (48)

82 (55)

 

25 to 30

94

39 (31)

7 (33)

48 (32)

 

>30

33

15 (12)

3 (14)

15 (10)

Plasma volume¤

< 3.5 ml

160

70 (55)

6 (29)

84 (56)

 

3.5 ml

139

58 (45)

15 (71)

66 (44)

  1. Data are n (%)
  2. # Former smokers and current smokers pooled
  3. ## Abuse: Women > 7 units per week, Men >14 units per week
  4. ### Underweight < 18,5, Normal 18,5–25, Overweight 25–30, Heavy overweight >30 ¤ median 3.0 ml, range (2–3.4 ml)
  5. NED No Evidence of Disease